Hydroquinone, Tretinoin and Fluocinolone Cream



















Cream Presentation

Each tube contains:
Hydroquinone 20 mg
Tretinoin 0.25 mg
Fluocinolone 0.1 mg










Hydroquinone is used topically which inhibits melanin production and shows potent antioxidant abilities. Tretinoin cures and reduces the intensity of marks by increasing collagen production in the dermis. Corticosteroid fluocinolone is combined with hydroquinone and tretinoin which reduces inflammation caused by them and also inhibits melanocyte metabolism.

Indication

  1. Scars
  2. Blotchy skin
  3. Skin problem

Mechanism of action

Melanin is a natural pigment which impart color to skin and is synthesized in specialized cytoplasmic organelles called melanosomes. Tyrosine is a precursor of melanin and within melanosome, it is converted to the active moiety by an enzyme called tyrosinase. The melanosomes are more active in the darker portion of the skin than those found in the normal areas of the body. The ingredients in cream not only counter melanosomes, but also the enzyme tyrosinase. Results will vary based on the individual's skin condition and the amount of skin exposure received. Initial improvement is often seen in just 2 weeks; full results generally appear after 2-3 months of regular use. Chlorocresol works as a preservative.

Side Effects

The product is possible safe for most adults. There is no disadvantage associated with the product if taken under the recommended usage however redness, irritation, burning sensation, mild skin rashes, sensitivity or thinning of skin may occur in some patients.

Interactions

  1. Using hydroquinone topical together with benzoyl peroxide, hydrogen peroxide, or other peroxide products may stain your skin
  2. Hair perming solutions, alcohol/lime/menthol-containing products (such as astringents, toners, shaving lotions), medicated or abrasive soaps and cleansers, products containing sulfur, resorcinol or salicylic acid, products containing alpha hydroxy acid can interact with Tretinoin
  3. Fluocinolone may react with corticosteroids taken by mouth (e.g., prednisone), other corticosteroids applied to the skin (e.g., hydrocortisone), drugs that lower the immune system (e.g., cyclosporine)

Precautions

  1. Prohibit sun radiation after applying this cream
  2. Immediately discontinue the use if hyper-sensitivity to any of the ingredients is noticed
  3. Protect your eyes and mouth
  4. Do not apply wounds or cuts
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